Study of the role of P2Y receptors in the development of experimental autoimmune uveitis.
نویسندگان
چکیده
During autoimmune uveitis (AU), retinal specific auto-reactive T lymphocytes (TL) are activated, alter blood retinal barrier and penetrate the eye where they start an inflammatory reaction. Nucleotides, normally present at low concentration in extracellular media, can act as a danger signal, through P2 receptors activation and might be implicated in AU. In this work we would like to investigate if the expression of the nucleotide receptor P2Y2 has any role in experimental autoimmune uveitis (EAU)
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عنوان ژورنال:
- Bulletin de la Societe belge d'ophtalmologie
دوره 317 شماره
صفحات -
تاریخ انتشار 2011